⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12334107 | 0.71 | — | — | |
| SCHEMBL23865488 | 0.64 | — | — | |
| SCHEMBL14652754 | 0.62 | — | — | |
| SCHEMBL17040512 | 0.60 | — | — | |
| SCHEMBL14621073 | 0.60 | PARP1 (0.36) | — | |
| SCHEMBL18945469 | 0.58 | — | — | |
| SCHEMBL17577901 | 0.58 | — | — | |
| SCHEMBL20374315 | 0.56 | — | — | |
| SCHEMBL9887337 | 0.56 | — | — | |
| SCHEMBL12674628 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434578-A1 | ARYLSULPHONYL-SUBSTITUTED TETRAHYDRO- AND HEXAHYDRO-CARBAZOLES AS 5-HT-6 RECEPTOR LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003030901-A1 | ARYLSULPHONYL-SUBSTITUTED TETRAHYDRO- AND HEXAHYDRO-CARBAZOLES AS 5-HT-6 RECEPTOR LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2003-04-17 | — | — | WO | disclosed |