Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17906 | 0.98 | MEN1 (0.52) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL6603412 | 0.96 | MEN1 (0.50) | MEN1KMT2AGAATDP1MAOA | |
| Ammonia Solution, Strong SCHEMBL28788409 | 0.96 | MEN1 (0.50) | MEN1KMT2AGAATDP1MAOA | |
| Bicarbonate SCHEMBL28028120 | 0.96 | MEN1 (0.50) | MEN1KMT2AGAATDP1MAOA | |
| Hydrochloric Acid SCHEMBL77819 | 0.96 | MEN1 (0.50) | MEN1KMT2AGAATDP1MAOA | |
| Methane SCHEMBL1486197 | 0.96 | MEN1 (0.50) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL9464092 | 0.96 | MEN1 (0.50) | MEN1KMT2AGAATDP1MAOA | |
| Bicarbonate SCHEMBL28028118 | 0.96 | MEN1 (0.50) | MEN1KMT2AGAATDP1MAOA | |
| Benzene SCHEMBL9601031 | 0.94 | MEN1 (0.49) | MEN1KMT2AGAATDP1MAOA | |
| Cyclopentane SCHEMBL8727534 | 0.92 | EPHX1 (0.49) | MEN1KMT2AGAATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105371-B1 | NOVEL ARYL SULPHONAMIDE AMINO ACID ESTERS AND ANALOGUES | BAYER HEALTHCARE AG (DE) | 2004-11-03 | — | — | EP | disclosed |
| EP-1105371-A2 | NOVEL ARYL SULPHONAMIDE AMINO ACID ESTERS AND ANALOGUES | BAYER AG (DE) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010968-A2 | NOVEL ARYL SULPHONAMIDE AMINO ACID ESTERS AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-02 | — | — | WO | disclosed |