Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 12/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6800868 | 0.87 | SLC2A1 (0.43) | SLC2A1ADRB3ADRB1ADRB2 | |
| SCHEMBL6800876 | 0.87 | SLC2A1 (0.43) | SLC2A1ADRB3ADRB1ADRB2 | |
| SCHEMBL4472057 | 0.86 | ADRB3 (0.45) | SLC2A1BACE1ADRB3ADRB1ADRB2 | |
| SCHEMBL4472051 | 0.86 | ADRB3 (0.45) | SLC2A1BACE1ADRB3ADRB1ADRB2 | |
| SCHEMBL6241306 | 0.86 | ADRB3 (0.45) | SLC2A1BACE1ADRB3ADRB1ADRB2 | |
| SCHEMBL6244538 | 0.85 | BACE1 (0.43) | SLC2A1BACE1ADRB3ADRB1ADRB2 | |
| SCHEMBL6677784 | 0.84 | BACE1 (0.43) | SLC2A1BACE1ADRB3ADRB1ADRB2 | |
| SCHEMBL6540709 | 0.84 | BACE1 (0.43) | SLC2A1BACE1ADRB3ADRB1ADRB2 | |
| SCHEMBL4462454 | 0.84 | BACE1 (0.43) | SLC2A1BACE1ADRB3ADRB1ADRB2 | |
| SCHEMBL6540704 | 0.84 | BACE1 (0.43) | SLC2A1BACE1ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |