Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | FABP1 | P07148 | 1/20 | 0.35 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677969 | 1.00 | HSP90AA1 (0.52) | HSP90AA1CCR6VDRMRGPRX4HSD17B2 | |
| SCHEMBL6680149 | 1.00 | HSP90AA1 (0.52) | HSP90AA1CCR6VDRMRGPRX4HSD17B2 | |
| Hydrochloric Acid SCHEMBL6716594 | 0.99 | HSP90AA1 (0.53) | HSP90AA1CCR6VDRMRGPRX4HSD17B2 | |
| Hydrochloric Acid SCHEMBL6716591 | 0.99 | HSP90AA1 (0.53) | HSP90AA1CCR6VDRMRGPRX4HSD17B2 | |
| Hydrochloric Acid SCHEMBL6724070 | 0.99 | HSP90AA1 (0.53) | HSP90AA1CCR6VDRMRGPRX4HSD17B2 | |
| SCHEMBL6683197 | 0.90 | HSP90AA1 (0.49) | HSP90AA1CCR6NPC1RAB9AMEN1 | |
| SCHEMBL6683199 | 0.90 | HSP90AA1 (0.49) | HSP90AA1CCR6NPC1RAB9AMEN1 | |
| SCHEMBL6677972 | 0.90 | HSP90AA1 (0.48) | HSP90AA1CCR6HSD17B2 | |
| SCHEMBL6722389 | 0.90 | HSP90AA1 (0.48) | HSP90AA1CCR6HSD17B2 | |
| SCHEMBL6677017 | 0.90 | HSP90AA1 (0.48) | HSP90AA1CCR6HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246793-B1 | SUBSTITUTED AMINOMETHYL-PHENYL-CYCLOHEXANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2004-11-10 | — | — | EP | claimed |
| US-6673794-B2 | ANALGESICS, INCOTINENCE, SKIN DISORDERS, ANTIINFLAMMATORY AGENTS | GRUENENTHAL GMBH (DE) | 2004-01-06 | — | — | US | claimed |
| US-20030069288-A1 | Substituted aminomethyl-phenyl-cyclohexane derivatives | GRUENETHAL GMBH (DE) | 2003-04-10 | — | — | US | claimed |
| US-6673794-B2 | ANALGESICS, INCOTINENCE, SKIN DISORDERS, ANTIINFLAMMATORY AGENTS | GRUENENTHAL GMBH (DE) | 2004-01-06 | — | — | US | disclosed |
| US-20030069288-A1 | Substituted aminomethyl-phenyl-cyclohexane derivatives | GRUENETHAL GMBH (DE) | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069288-A1 | Substituted aminomethyl-phenyl-cyclohexane derivatives | PTGER1, CYP2E1, HRH2 | HSP90AA1 1652/4885CCR6 1317/4885VDR 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.