Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CDC25C | P30307 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632993 | 0.81 | KMT2A (0.58) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1855124 | 0.80 | KMT2A (0.56) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL16790601 | 0.78 | KMT2A (0.55) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL4573216 | 0.78 | KMT2A (0.58) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL3001943 | 0.78 | KMT2A (0.58) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL19900671 | 0.76 | KMT2A (0.78) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL19941393 | 0.74 | KMT2A (0.50) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL219769 | 0.74 | KMT2A (0.58) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL95791 | 0.74 | KMT2A (0.58) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL95792 | 0.74 | KMT2A (0.58) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446110-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | Structural Bioinformatics Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003032916-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | STRUCTURAL BIOINFORMATICS INC. (US) | 2003-04-24 | — | — | WO | disclosed |