SCHEMBL6680893

SCHEMBL6680893

Cc1nc(N)c2nc(C)n(CC[AsH2])c2c1C

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 2/20 0.37
CSNK2A1 P68400 4/20 0.36
PIM1 P11309 1/20 0.36
CSNK2A2 P19784 1/20 0.36
CSNK2B P67870 1/20 0.36
CSNK2A3 Q8NEV1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6095631 0.85 CSNK2A1 (0.43) TLR7CSNK2A1PIM1CSNK2A2CSNK2B
Hydrochloric Acid SCHEMBL6097166 0.84 CSNK2A1 (0.42) TLR7CSNK2A1PIM1CSNK2A2CSNK2B
SCHEMBL6097458 0.83 CSNK2A1 (0.55) TLR7CSNK2A1PIM1CSNK2A2CSNK2B
SCHEMBL4793038 0.79 CSNK2A1 (0.38) TLR7CSNK2A1PIM1CSNK2A2CSNK2B
SCHEMBL4794033 0.78 CSNK2A1 (0.38) TLR7CSNK2A1PIM1CSNK2A2CSNK2B
SCHEMBL4790972 0.78 CSNK2A1 (0.38) TLR7CSNK2A1PIM1CSNK2A2CSNK2B
SCHEMBL4792194 0.78 TLR8 (0.43) TLR7CSNK2A1PIM1CSNK2A2CSNK2B
SCHEMBL8113615 0.77 TLR7 (0.40) TLR7
SCHEMBL4791595 0.77 CSNK2A1 (0.37) TLR7CSNK2A1PIM1CSNK2A2CSNK2B
SCHEMBL5339643 0.77 CSNK2A1 (0.37) TLR7CSNK2A1PIM1CSNK2A2CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1453829-A1 SULFONAMIDO SUBSTITUTED IMIDAZOPYRIDINES 3M Innovative Properties Company (US) 2004-09-08 EP disclosed
EP-1451186-A2 UREA SUBSTITUTED IMIDAZOPYRIDINES 3M Innovative Properties Company (US) 2004-09-01 EP disclosed
WO-2003050117-A1 SULFONAMIDO SUBSTITUTED IMIDAZOPYRIDINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-06-19 WO disclosed
WO-2003050119-A2 UREA SUBSTITUTED IMIDAZOPYRIDINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-06-19 WO disclosed