Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.45 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.45 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15265215 | 0.90 | MAPT (0.53) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL669313 | 0.86 | MAPT (0.59) | MAPTMEN1KMT2AL3MBTL1POLB | |
| Methane SCHEMBL9392239 | 0.85 | MAPT (0.57) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL10858330 | 0.83 | MAPT (0.56) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL126110 | 0.81 | MAPT (0.61) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL15264825 | 0.81 | MEN1 (0.53) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL29042545 | 0.80 | MEN1 (0.56) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL718255 | 0.80 | MAPT (0.74) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL5964901 | 0.79 | MAPT (0.59) | MAPTMEN1KMT2AL3MBTL1POLB | |
| SCHEMBL11691634 | 0.79 | MAPT (0.64) | MAPTMEN1KMT2AL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024558-A2 | LIGHT MEDIATED REGULATION OF PROTEIN DIMERIZATION | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-02-23 | — | — | WO | disclosed |