SCHEMBL6681841

SCHEMBL6681841

O=C(c1ccccc1)c1ccccc1NC(Cc1ccc(OCCN2c3ccccc3C=Cc3ccccc32)cc1)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.70
PPARA Q07869 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6634323 1.00 PPARG (0.70) PPARGPPARA
SCHEMBL6635105 0.92 PPARG (0.61) PPARGPPARA
SCHEMBL6679623 0.92 PPARG (0.61) PPARGPPARA
SCHEMBL6636646 0.88 PPARG (0.66) PPARGPPARA
SCHEMBL6638840 0.88 PPARG (0.66) PPARGPPARA
SCHEMBL2786676 0.88 PPARG (0.66) PPARGPPARA
SCHEMBL2786576 0.85 PPARG (0.64) PPARGPPARA
SCHEMBL2787981 0.82 PPARG (0.71) PPARGPPARA
SCHEMBL6637182 0.82 PPARG (0.71) PPARGPPARA
SCHEMBL6636947 0.82 PPARG (0.64) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1414806-A1 NOVEL VINYL N-(2-BENZOYLPHENYL)-L-TYROSINE DERIVATIVES AND THEIR USE AS ANTIDIABETICS ETC NOVO NORDISK A/S (DK) 2004-05-06 EP claimed
WO-2003011834-A1 NOVEL VINYL N-(2-BENZOYLPHENYL)-L-TYROSINE DERIVATIVES AND THEIR USE AS ANTIDIABETICS ETC NOVO NORDISK A/S (DK) 2003-02-13 WO claimed