Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 17/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680863 | 0.94 | ADRB3 (0.47) | ADRB3ADRB1P2RX3 | |
| SCHEMBL6677317 | 0.93 | ADRB3 (0.57) | ADRB3ADRB1 | |
| SCHEMBL6243522 | 0.89 | ADRB3 (0.53) | ADRB3ADRB1SLC2A1 | |
| SCHEMBL6677819 | 0.84 | ADRB3 (0.40) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6677352 | 0.83 | ADRB3 (0.52) | ADRB3ADRB1 | |
| SCHEMBL6679264 | 0.81 | ADRB3 (0.36) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6239033 | 0.81 | ADRB3 (0.44) | ADRB3ADRB1P2RX3SLC2A1ADRB2 | |
| SCHEMBL6243606 | 0.80 | ADRB3 (0.51) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6244119 | 0.80 | ADRB3 (0.61) | ADRB3ADRB1SLC2A1ADRB2 | |
| SCHEMBL6682294 | 0.80 | ADRB3 (0.47) | ADRB3ADRB1SLC2A1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |