Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718654 | 0.80 | KDM4E (0.46) | KDM4EPOLBALDH1A1MAOBSLC6A2 | |
| SCHEMBL28114670 | 0.78 | KDM4E (0.51) | KDM4EPOLBALDH1A1SLC6A2SLC6A3 | |
| SCHEMBL8486486 | 0.77 | CES1 (0.56) | LMNAALDH1A1ESR1ESR2TSHR | |
| SCHEMBL11880866 | 0.76 | TSHR (0.52) | LMNAKDM4EPOLBALDH1A1MAOB | |
| SCHEMBL31397663 | 0.76 | KDM4E (0.51) | KDM4EPOLBALDH1A1MAOBSLC6A2 | |
| SCHEMBL15012155 | 0.74 | KDM4E (0.50) | KDM4EPOLBALDH1A1MAOBSLC6A2 | |
| SCHEMBL15012407 | 0.74 | KDM4E (0.50) | KDM4EPOLBALDH1A1MAOBSLC6A2 | |
| SCHEMBL1691754 | 0.74 | KDM4E (0.53) | KDM4EPOLBALDH1A1MAOBSLC6A2 | |
| SCHEMBL13557891 | 0.73 | KDM4E (0.56) | LMNAKDM4EPOLBALDH1A1SLC6A2 | |
| SCHEMBL95926 | 0.73 | KDM4E (0.56) | LMNAKDM4EPOLBALDH1A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046080-A1 | METHOD OF PREPARATION OF DERIVATIVES OF SUBSTITUTED 2-ARYL AIKANOIC ACIDS | ZENTIVA, A.S. (SK) | 2004-06-03 | — | — | WO | disclosed |