SCHEMBL6682771

SCHEMBL6682771

CCCCCC(CC)NC(=O)[C@@H](N)Cc1c[nH]cn1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 10/20 0.36
DPP9 Q86TI2 8/20 0.36
DPP8 Q6V1X1 7/20 0.36
DPP4 P27487 5/20 0.36
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33
HRH3 Q9Y5N1 6/20 0.32
HRH4 Q9H3N8 2/20 0.32
SPHK1 Q9NYA1 1/20 0.32
TLR2 O60603 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10422576 0.91 PLA2G10 (0.38) DPP7DPP9DPP8DPP4GNAI3
SCHEMBL17941641 0.81 DPP7 (0.50) DPP7GNAI3GNAO1GNAI1
SCHEMBL24420714 0.81 DPP7 (0.50) DPP7GNAI3GNAO1GNAI1
SCHEMBL25122226 0.81 DPP7 (0.50) DPP7GNAI3GNAO1GNAI1
SCHEMBL31729502 0.81 DPP7 (0.50) DPP7GNAI3GNAO1GNAI1
SCHEMBL25122498 0.81 DPP7 (0.50) DPP7GNAI3GNAO1GNAI1
SCHEMBL23007713 0.81 DPP7 (0.50) DPP7GNAI3GNAO1GNAI1
SCHEMBL17941643 0.81 DPP7 (0.50) DPP7GNAI3GNAO1GNAI1
SCHEMBL12952431 0.80 DPP7 (0.46) DPP7GNAI3GNAO1GNAI1
SCHEMBL18819993 0.80 GRIK1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1473347-A1 Core/shell nanoparticles suitable for (F) RET-assays Nanosolutions GmbH (DE) 2004-11-03 EP disclosed