SCHEMBL6682773

SCHEMBL6682773

CCC(C)(C)c1ccc(OC[O])c(C(C)(C)CC)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.63
NPSR1 Q6W5P4 5/20 0.63
SMN1; SMN2 Q16637 5/20 0.63
MEN1 O00255 4/20 0.63
KMT2A Q03164 4/20 0.63
ALDH1A1 P00352 2/20 0.63
MAPT P10636 5/20 0.54
HTT P42858 3/20 0.54
UBE2N P61088 2/20 0.54
GLA P06280 1/20 0.54
MITF O75030 1/20 0.54
RAB9A P51151 4/20 0.52
RAD52 P43351 2/20 0.52
APAF1 O14727 1/20 0.52
HSP90AA1 P07900 1/20 0.52
NOD2 Q9HC29 1/20 0.52
STAT3 P40763 1/20 0.49
RCE1 Q9Y256 1/20 0.49
NPC1 O15118 3/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL76971 0.87 MAPK1 (0.62) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8470405 0.86 MAPK1 (0.67) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL7767137 0.86 MAPK1 (0.61) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL6536664 0.84 MAPK1 (0.63) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL5145870 0.83 MAPK1 (0.61) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL6682777 0.83 MAPK1 (0.63) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8598929 0.83 MAPK1 (0.59) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL7240794 0.83 MAPK1 (0.59) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL7240787 0.83 MAPK1 (0.75) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL75920 0.83 MAPK1 (0.59) MAPK1NPSR1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1132770-B1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 2004-11-17 EP disclosed
US-6468729-B2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2002-10-22 US disclosed
US-20010031433-A1 Silver halide photographic light-sensitive material FUJIFILM CORPORATION (JP) 2001-10-18 US disclosed
EP-1132770-A2 Silver halide photographic light-sensitive material Fuji Photo Film Co., Ltd. (JP) 2001-09-12 EP disclosed