Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 20/20 | 0.64 |
| ▸ | HCRTR2 | O43614 | 14/20 | 0.64 |
| ▸ | TSPO | P30536 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1777641 | 1.00 | HCRTR1 (0.64) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1778399 | 0.98 | HCRTR1 (0.62) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1778402 | 0.98 | HCRTR1 (0.62) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1777655 | 0.95 | HCRTR2 (0.59) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1778902 | 0.93 | HCRTR1 (0.64) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1777725 | 0.91 | HCRTR1 (0.63) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1776015 | 0.89 | HCRTR1 (0.60) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1779440 | 0.88 | HCRTR1 (0.51) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1778578 | 0.86 | HCRTR1 (0.77) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1776427 | 0.86 | HCRTR1 (0.66) | HCRTR1HCRTR2TSPOOPRK1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406897-A2 | COMPOUNDS | SmithKline Beecham plc (GB) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003002559-A2 | PIPERIDINE COMPOUNDS FOR USE AS OREXIN RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-01-09 | — | — | WO | disclosed |