SCHEMBL6683597

SCHEMBL6683597

S=P(SS)(SCc1ccccc1)SCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
CTSL P07711 1/20 0.38
CTSB P07858 1/20 0.38
EPHX2 P34913 1/20 0.37
IDO1 P14902 4/20 0.36
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
NOS2 P35228 1/20 0.36
POLB P06746 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MAOB P27338 1/20 0.34
MGLL Q99685 1/20 0.34
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
ALOX12 P18054 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14445184 0.79 CA12 (0.38) CA12CA1CA2CA9CTSL
SCHEMBL3074312 0.79 CA12 (0.35) CA12CA1CA2CA9CTSL
SCHEMBL3078061 0.78 CA12 (0.41) CA12CA1CA2CA9CTSL
SCHEMBL3081281 0.78 CA12 (0.41) CA12CA1CA2CA9CTSL
SCHEMBL7074459 0.75 CA12 (0.42) CA12CA1CA2CA9CTSL
SCHEMBL3071085 0.75 CA12 (0.38) CA12CA1CA2CA9CTSL
SCHEMBL3073136 0.75 IDO1 (0.41) CA12CA1CA2CA9CTSL
SCHEMBL3062175 0.74 TSHR (0.41) CA12CA1CA2CA9IDO1
SCHEMBL8469287 0.74 CA12 (0.45) CA12CA1CA2CA9CTSL
SCHEMBL3064447 0.74 POLB (0.47) CA12CA1CA2CA9IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004065305-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE UNIVERSITY OF DAYTON (US) 2004-08-05 WO disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed