Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458164 | 0.77 | TSHR (0.51) | LMNATSHRMAPTNPC1RAB9A | |
| SCHEMBL6738366 | 0.73 | TSHR (0.76) | LMNATSHRMAPTNPC1RAB9A | |
| SCHEMBL11392466 | 0.71 | TSHR (0.73) | LMNATSHRMAPTNPC1RAB9A | |
| Iodide SCHEMBL28598177 | 0.71 | TSHR (0.73) | LMNATSHRMAPTNPC1RAB9A | |
| Iodide SCHEMBL30804629 | 0.71 | TSHR (0.73) | LMNATSHRMAPTNPC1RAB9A | |
| SCHEMBL11392461 | 0.71 | TSHR (0.73) | LMNATSHRMAPTNPC1RAB9A | |
| SCHEMBL28471286 | 0.71 | TSHR (0.73) | LMNATSHRMAPTNPC1RAB9A | |
| SCHEMBL2851056 | 0.71 | NPC1 (0.51) | LMNATSHRMAPTNPC1RAB9A | |
| SCHEMBL1478380 | 0.70 | MAPT (0.66) | LMNATSHRMAPTNPC1RAB9A | |
| SCHEMBL13118928 | 0.70 | TSHR (0.50) | LMNATSHRMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024755-A2 | SARCOLYSYL DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF | LIPAL BIOCHEMICALS AG (CH) | 2004-03-25 | — | — | WO | disclosed |