Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 3/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 13/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622131 | 0.88 | SIRT2 (0.41) | SIRT2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8624874 | 0.86 | SIRT2 (0.43) | SIRT2CETPCYP19A1PTPN1ACP1 | |
| SCHEMBL5697005 | 0.85 | SIRT2 (0.39) | SIRT2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5803979 | 0.84 | GRIN1 (0.36) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8622049 | 0.83 | SIRT2 (0.35) | SIRT2GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL28301399 | 0.83 | GRIN2D (0.35) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8622095 | 0.83 | SIRT2 (0.45) | SIRT2CYP19A1PTPN1ACP1CDC25B | |
| SCHEMBL8621156 | 0.81 | SIRT2 (0.47) | SIRT2CYP19A1PTPN1ACP1CDC25B | |
| SCHEMBL6909148 | 0.81 | SIRT2 (0.49) | SIRT2CETPPTPN1ACP1CDC25B | |
| SCHEMBL28209529 | 0.79 | SIRT2 (0.35) | SIRT2GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438284-A1 | SYNTHESIS OF ( )-2-((DIMETHYLAMINO)METHYL)-1-(ARYL)CYCLOHEXANOLS | EURO-CELTIQUE S.A. (LU) | 2004-07-21 | — | — | EP | claimed |
| WO-2003029186-A1 | SYNTHESIS OF (±)-2-((DIMETHYLAMINO)METHYL)-1-(ARYL)CYCLOHEXANOLS | EURO-CELTIQUE, S.A. (LU) | 2003-04-10 | — | — | WO | claimed |
| EP-1438284-A1 | SYNTHESIS OF ( )-2-((DIMETHYLAMINO)METHYL)-1-(ARYL)CYCLOHEXANOLS | EURO-CELTIQUE S.A. (LU) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003029186-A1 | SYNTHESIS OF (±)-2-((DIMETHYLAMINO)METHYL)-1-(ARYL)CYCLOHEXANOLS | EURO-CELTIQUE, S.A. (LU) | 2003-04-10 | — | — | WO | disclosed |