Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 12/20 | 0.57 |
| ▸ | DPP9 | Q86TI2 | 10/20 | 0.57 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.57 |
| ▸ | FAP | Q12884 | 5/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685328 | 0.83 | DPP4 (0.58) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6688077 | 0.81 | DPP4 (0.48) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6689703 | 0.81 | DPP4 (0.72) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6688921 | 0.79 | DPP4 (0.63) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6686205 | 0.78 | DPP4 (0.62) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6692186 | 0.78 | DPP4 (0.62) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6686202 | 0.78 | DPP4 (0.61) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL6685461 | 0.77 | PREP (0.58) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL6693335 | 0.77 | DPP4 (0.65) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL5228430 | 0.77 | DPP4 (0.73) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089362-A1 | 2-CYANOPYRROLES AND THEIR ANALOGUES AS DDP-IV INHIBITORS | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | disclosed |