Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 9/20 | 0.52 |
| ▸ | PPIA | P62937 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685627 | 0.88 | PTGER1 (0.67) | PTGER1CYP2C9MRGPRX4 | |
| SCHEMBL5110014 | 0.83 | PTGER1 (0.74) | PTGER1PPIANPC1ALDH1A1RAB9A | |
| SCHEMBL6690443 | 0.79 | PTGER1 (0.67) | PTGER1CYP2C9MRGPRX4 | |
| SCHEMBL4886525 | 0.78 | PTGER1 (0.63) | PTGER1PPIANPC1ALDH1A1RAB9A | |
| SCHEMBL5099258 | 0.78 | PTGER1 (0.77) | PTGER1CYP2C9 | |
| SCHEMBL5621051 | 0.78 | PTGER1 (0.77) | PTGER1CYP2C9 | |
| SCHEMBL4880247 | 0.77 | PTGER1 (0.79) | PTGER1PPIACYP2C9 | |
| SCHEMBL5155213 | 0.75 | PTGER1 (0.79) | PTGER1CYP2C9MRGPRX4 | |
| SCHEMBL5102961 | 0.74 | PTGER1 (0.57) | PTGER1PPIACYP2C9 | |
| SCHEMBL3911336 | 0.74 | MRGPRX4 (0.62) | NPC1ALDH1A1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004083185-A2 | PHENYL SUBSTITUTED IMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2004-09-30 | — | — | WO | disclosed |