SCHEMBL6684822

SCHEMBL6684822

CCCCCCCC(Cl)(Br)c1cccc2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.38
NPC1 O15118 4/20 0.38
ALDH1A1 P00352 4/20 0.38
GAA P10253 4/20 0.38
HTT P42858 4/20 0.38
RAB9A P51151 4/20 0.38
SMN1; SMN2 Q16637 4/20 0.38
KMT2A Q03164 4/20 0.38
MEN1 O00255 3/20 0.38
NPSR1 Q6W5P4 2/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
HPGD P15428 1/20 0.38
CYP2C19 P33261 1/20 0.38
MAPK1 P28482 1/20 0.38
RAD52 P43351 1/20 0.38
CHAT P28329 1/20 0.37
CNR1 P21554 3/20 0.36
CNR2 P34972 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6680367 1.00 KDM4E (0.38) KDM4ENPC1ALDH1A1GAAHTT
SCHEMBL6686396 0.98 KDM4E (0.36) KDM4ENPC1ALDH1A1GAAHTT
SCHEMBL6682140 0.94 HTR1B (0.37) KDM4ENPC1ALDH1A1GAAHTT
SCHEMBL6685050 0.87 CYP2A6 (0.36) KDM4EALDH1A1LMNACYP1A2CYP2D6
SCHEMBL6686907 0.86 KDM4E (0.38) KDM4ENPC1ALDH1A1GAAHTT
SCHEMBL6682626 0.86 KDM4E (0.38) KDM4ENPC1ALDH1A1GAAHTT
SCHEMBL6685429 0.84 KDM4E (0.39) KDM4ENPC1ALDH1A1GAAHTT
SCHEMBL6681394 0.84 KDM4E (0.39) KDM4ENPC1ALDH1A1GAAHTT
SCHEMBL28281175 0.84 KDM4E (0.39) KDM4ENPC1ALDH1A1GAAHTT
SCHEMBL6681462 0.84 KDM4E (0.37) KDM4ENPC1ALDH1A1GAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed