SCHEMBL6684987

SCHEMBL6684987

C=C(C)C1CC=C(C(=O)N(CC)CC)CC1

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.63
LMNA P02545 2/20 0.63
ALOX15 P16050 3/20 0.49
ALDH1A1 P00352 3/20 0.49
CYP1B1 Q16678 1/20 0.49
TRPA1 O75762 1/20 0.48
TRPV1 Q8NER1 1/20 0.43
MAPK1 P28482 1/20 0.43
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
RAB9A P51151 1/20 0.37
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6684148 0.89 TSHR (0.60) TSHRLMNAALOX15ALDH1A1CYP1B1
SCHEMBL6683680 0.83 TSHR (0.69) TSHRLMNAALOX15ALDH1A1CYP1B1
SCHEMBL6685127 0.80 TSHR (0.59) TSHRLMNAALOX15ALDH1A1CYP1B1
SCHEMBL13301247 0.79 TSHR (0.77) TSHRLMNAALOX15ALDH1A1CYP1B1
SCHEMBL14626987 0.79 TSHR (0.77) TSHRLMNAALOX15ALDH1A1CYP1B1
Perillic Acid SCHEMBL19341660 0.78 TSHR (1.00) TSHRLMNAALOX15ALDH1A1CYP1B1
Perillic Acid SCHEMBL465998 0.78 TSHR (1.00) TSHRLMNAALOX15ALDH1A1CYP1B1
Perillic Acid SCHEMBL8434974 0.78 TSHR (1.00) TSHRLMNAALOX15ALDH1A1CYP1B1
Perillic Acid (-) SCHEMBL19341659 0.78 TSHR (1.00) TSHRLMNAALOX15ALDH1A1CYP1B1
SCHEMBL6687180 0.77 TSHR (0.63) TSHRLMNAALOX15ALDH1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004076400-A1 ANTIMICROBIAL AGENT AGAINST BACTERIA, YEAST AND MOULDS DR. RIEKS GMBH (DE) 2004-09-10 WO claimed
WO-2004076400-A1 ANTIMICROBIAL AGENT AGAINST BACTERIA, YEAST AND MOULDS DR. RIEKS GMBH (DE) 2004-09-10 WO disclosed