Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 20/20 | 0.60 |
| ▸ | HCRTR2 | O43614 | 15/20 | 0.60 |
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1778604 | 1.00 | HCRTR1 (0.60) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1777548 | 0.92 | HCRTR1 (0.60) | HCRTR1HCRTR2 | |
| SCHEMBL1778797 | 0.92 | HCRTR1 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL1779324 | 0.92 | HCRTR1 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL1778624 | 0.91 | HCRTR1 (0.64) | HCRTR1HCRTR2 | |
| SCHEMBL6692756 | 0.91 | HCRTR1 (0.64) | HCRTR1HCRTR2 | |
| SCHEMBL1777329 | 0.90 | HCRTR1 (0.60) | HCRTR1HCRTR2 | |
| SCHEMBL1780233 | 0.87 | HCRTR1 (0.58) | HCRTR1HCRTR2 | |
| SCHEMBL1780504 | 0.85 | HCRTR1 (0.54) | HCRTR1HCRTR2 | |
| SCHEMBL1256951 | 0.84 | HCRTR1 (0.66) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406897-A2 | COMPOUNDS | SmithKline Beecham plc (GB) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003002559-A2 | PIPERIDINE COMPOUNDS FOR USE AS OREXIN RECEPTOR ANTAGONIST | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-01-09 | — | — | WO | disclosed |