SCHEMBL6685351

SCHEMBL6685351

N#CC1CCCN1C(=O)CC(N)C1CCNCC1

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PREP P48147 3/20 0.56
DPP4 P27487 17/20 0.51
DPP8 Q6V1X1 3/20 0.51
DPP9 Q86TI2 2/20 0.51
DPP7 Q9UHL4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6693011 0.91 DPP4 (0.57) PREPDPP4DPP8DPP9DPP7
SCHEMBL6695970 0.89 DPP4 (0.63) PREPDPP4DPP8DPP9DPP7
SCHEMBL6690401 0.88 DPP4 (0.64) PREPDPP4DPP8DPP9DPP7
SCHEMBL6687597 0.88 DPP4 (0.64) PREPDPP4DPP8DPP9DPP7
SCHEMBL6686202 0.81 DPP4 (0.61) PREPDPP4DPP8DPP9DPP7
SCHEMBL6693748 0.79 DPP4 (0.51) PREPDPP4DPP8DPP9DPP7
SCHEMBL3815993 0.76 DPP4 (0.82) PREPDPP4DPP8DPP9
SCHEMBL3815997 0.76 DPP4 (0.82) PREPDPP4DPP8DPP9
SCHEMBL6686973 0.76 DPP4 (0.63) PREPDPP4DPP8DPP9
SCHEMBL6685366 0.74 DPP4 (0.59) PREPDPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004089362-A1 2-CYANOPYRROLES AND THEIR ANALOGUES AS DDP-IV INHIBITORS NOVO NORDISK A/S (DK) 2004-10-21 WO disclosed