SCHEMBL6685358

SCHEMBL6685358

CCCCCCCC(Br)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.45
CSNK1E P49674 1/20 0.44
CYP19A1 P11511 3/20 0.43
SIGMAR1 Q99720 1/20 0.43
NAAA Q02083 2/20 0.42
LCK P06239 1/20 0.42
PPARD Q03181 1/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.42
ZDHHC2 Q9UIJ5 1/20 0.42
OPRM1 P35372 2/20 0.42
OPRD1 P41143 2/20 0.42
OPRK1 P41145 2/20 0.42
OPRL1 P41146 2/20 0.42
KCNH2 Q12809 2/20 0.41
ASAH1 Q13510 2/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
ALDH1A1 P00352 2/20 0.40
ACER2 Q5QJU3 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27806681 1.00 HTR2A (0.45) HTR2ACSNK1ECYP19A1SIGMAR1NAAA
SCHEMBL7573099 1.00 HTR2A (0.45) HTR2ACSNK1ECYP19A1SIGMAR1NAAA
SCHEMBL27692872 1.00 HTR2A (0.45) HTR2ACSNK1ECYP19A1SIGMAR1NAAA
SCHEMBL11806604 1.00 HTR2A (0.45) HTR2ACSNK1ECYP19A1SIGMAR1NAAA
SCHEMBL2404354 1.00 HTR2A (0.45) HTR2ACSNK1ECYP19A1SIGMAR1NAAA
SCHEMBL6681848 1.00 HTR2A (0.45) HTR2ACSNK1ECYP19A1SIGMAR1NAAA
SCHEMBL14636124 1.00 HTR2A (0.45) HTR2ACSNK1ECYP19A1SIGMAR1NAAA
SCHEMBL8728015 1.00 HTR2A (0.45) HTR2ACSNK1ECYP19A1SIGMAR1NAAA
SCHEMBL22734895 1.00 HTR2A (0.45) HTR2ACSNK1ECYP19A1SIGMAR1NAAA
SCHEMBL28516127 0.98 HTR2A (0.44) HTR2ACSNK1ECYP19A1SIGMAR1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110328373-B Preparation method of small-size gold nanorods 广州珂纳偲生物技术有限公司 2022-05-03 CN disclosed
US-10421779-B2 Carbazole compound having anti-virus activity KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2019-09-24 US disclosed
CN-109328189-A Condensed dithienothiophene derivative is used as organic semi-conductor purposes with it 默克专利股份有限公司 2019-02-12 CN disclosed
CN-108366990-A Synthetic sphingolipid molecules, drugs, methods of their synthesis and methods of treatment 加利福尼亚大学董事会 2018-08-03 CN disclosed
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-01 US disclosed
US-9475697-B2 Removal of bromine from gaseous hydrogen bromide ALBEMARLE CORPORATION (US) 2016-10-25 US disclosed
US-20150147265-A1 Removal of Bromine From Gaseous Hydrogen Bromide ALBEMARLE CORPORATION 2015-05-28 US disclosed
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed
EP-0738144-A4 PHENYLMETHYL HEXANAMIDES, AND THE USE THEREOF SMITHKLINE BEECHAM CORP (US) 1999-06-30 EP disclosed
EP-0738144-A1 PHENYLMETHYL HEXANAMIDES, AND THE USE THEREOF SMITHKLINE BEECHAM CORPORATION (US) 1996-10-23 EP disclosed
WO-1995017888-A1 PHENYLMETHYL HEXANAMIDES, AND THE USE THEREOF SMITHKLINE BEECHAM CORPORATION (US) 1995-07-06 WO disclosed
EP-0375348-A1 Leukotriene antagonists SMITHKLINE BEECHAM CORPORATION (US) 1990-06-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY ZC3HAV1, ZC3HAV1L, GTF3C3 HTR2A 4713/4885CSNK1E 175/4885CYP19A1 2916/4885
US-10421779-B2 Carbazole compound having anti-virus activity ZC3HAV1, ZC3HAV1L, GTF3C3 HTR2A 4713/4885CSNK1E 175/4885CYP19A1 2916/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.