Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.55 |
| ▸ | BCR | P11274 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30489763 | 1.00 | ABL1 (0.55) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL29968150 | 1.00 | ABL1 (0.55) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL6686384 | 1.00 | ABL1 (0.55) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL7913407 | 1.00 | ABL1 (0.55) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL11045692 | 0.95 | ABL1 (0.50) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL10601690 | 0.95 | ABL1 (0.50) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL11154713 | 0.95 | ABL1 (0.50) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL8744514 | 0.95 | ABL1 (0.50) | ABL1ABCB1BCRNPC1RAB9A | |
| Perchlorate SCHEMBL7903126 | 0.93 | NPC1 (0.61) | ABL1ABCB1BCRNPC1RAB9A | |
| Perchlorate SCHEMBL9175221 | 0.93 | NPC1 (0.61) | ABL1ABCB1BCRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084126-B1 | NOVEL VINCA-ALKALOID DERIVATIVES AND PREPARATION METHOD | ROOWIN S A (FR) | 2004-11-17 | — | — | EP | claimed |
| US-6365735-B1 | ALKALOIDS FORMED BY REDUCTION OR CYANATION | ROOWIN S.A. (FR) | 2002-04-02 | — | — | US | claimed |
| EP-1084126-A1 | NOVEL VINCA-ALKALOID DERIVATIVES AND PREPARATION METHOD | Roowin, S.A. (FR) | 2001-03-21 | — | — | EP | claimed |
| WO-1999062912-A1 | NOVEL VINCA-ALKALOID DERIVATIVES AND PREPARATION METHOD | ROOWIN S.A. (FR) | 1999-12-09 | — | — | WO | claimed |
| EP-0196561-B1 | PHOTOSENSITIVE LITHOGRAPHIC PRINTING PLATE | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-06-14 | — | — | EP | claimed |
| US-20110318689-A1 | LIGHT-SENSITIVE LITHOGRAPHIC PRINTING PLATE MATERIAL | MITSUBISHI PAPER MILLS LIMITED (JP) | 2011-12-29 | — | — | US | disclosed |
| EP-1084126-B1 | NOVEL VINCA-ALKALOID DERIVATIVES AND PREPARATION METHOD | ROOWIN S A (FR) | 2004-11-17 | — | — | EP | disclosed |
| US-6365735-B1 | ALKALOIDS FORMED BY REDUCTION OR CYANATION | ROOWIN S.A. (FR) | 2002-04-02 | — | — | US | disclosed |
| EP-1084126-A1 | NOVEL VINCA-ALKALOID DERIVATIVES AND PREPARATION METHOD | Roowin, S.A. (FR) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999062912-A1 | NOVEL VINCA-ALKALOID DERIVATIVES AND PREPARATION METHOD | ROOWIN S.A. (FR) | 1999-12-09 | — | — | WO | disclosed |