Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 4/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,5-Pentanediol SCHEMBL6688362 | 1.00 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4MAPT | |
| SCHEMBL35200 | 0.89 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4MAPT | |
| SCHEMBL29362562 | 0.89 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4MAPT | |
| SCHEMBL15243937 | 0.89 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4MAPT | |
| SCHEMBL7143775 | 0.87 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4MAPT | |
| SCHEMBL19845032 | 0.85 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4MAPT | |
| Acetic Acid SCHEMBL28264238 | 0.84 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4MAPT | |
| Acrylamide SCHEMBL7156408 | 0.83 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4MAPT | |
| SCHEMBL4667860 | 0.81 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL23494022 | 0.81 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046803-A1 | LIQUID CRYSTAL DEVICES WITH REDUCED SURFACE ANCHORING ENERGY | QINETIQ LIMITED (GB) | 2004-06-03 | — | — | WO | disclosed |
| EP-1046078-A1 | LIQUID CRYSTAL DEVICE ALIGNMENT | Hewlett-Packard Company (US) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999018474-A1 | LIQUID CRYSTAL DEVICE ALIGNMENT | HEWLETT-PACKARD COMPANY (US) | 1999-04-15 | — | — | WO | disclosed |