Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 5/20 | 0.31 |
| ▸ | CTSL | P07711 | 3/20 | 0.31 |
| ▸ | CTSB | P07858 | 2/20 | 0.30 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6685619 | 0.88 | TUBB1 (0.42) | TUBB1CTSSCTSLCTSBCTSK | |
| Trifluoroacetic Acid SCHEMBL6806874 | 0.88 | TUBB1 (0.57) | TUBB1CTSSCTSL | |
| SCHEMBL6802822 | 0.83 | TUBB1 (0.61) | TUBB1CTSSCTSLCTSBCTSK | |
| Trifluoroacetic Acid SCHEMBL6809618 | 0.76 | TUBB1 (0.60) | TUBB1 | |
| Trifluoroacetic Acid SCHEMBL6674557 | 0.74 | TUBB1 (0.64) | TUBB1 | |
| Trifluoroacetic Acid SCHEMBL6674546 | 0.74 | TUBB1 (0.64) | TUBB1 | |
| SCHEMBL6801949 | 0.73 | TUBB1 (0.62) | TUBB1 | |
| Taltobulin SCHEMBL30483111 | 0.72 | TUBB1 (0.74) | TUBB1 | |
| SCHEMBL6802182 | 0.71 | TUBB1 (0.64) | TUBB1 | |
| Trifluoroacetic Acid SCHEMBL6671681 | 0.71 | TUBB1 (0.64) | TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026293-A2 | HEMIASTERLIN DERIVATIVES FOR TREATING RESISTANT TUMORS | WYETH HOLDINGS CORPORATION (US) | 2004-04-01 | — | — | WO | disclosed |