Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.45 |
| ▸ | PREP | P48147 | 6/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692042 | 0.83 | DPP4 (0.46) | DPP4DPP8PREPDPP9 | |
| SCHEMBL6687279 | 0.78 | DPP4 (0.50) | DPP4DPP8PREPDPP7DPP9 | |
| SCHEMBL5529957 | 0.77 | DPP4 (0.59) | DPP4DPP8PREPDPP7DPP9 | |
| SCHEMBL9129667 | 0.77 | RET (0.45) | — | |
| SCHEMBL739456 | 0.75 | SUCNR1 (0.49) | ITGB3ITGA2B | |
| SCHEMBL739452 | 0.75 | SUCNR1 (0.49) | ITGB3ITGA2B | |
| SCHEMBL6692023 | 0.75 | DPP4 (0.53) | DPP4DPP8PREP | |
| SCHEMBL6689969 | 0.75 | DPP4 (0.50) | DPP4DPP8PREP | |
| SCHEMBL6692019 | 0.75 | DPP4 (0.53) | DPP4DPP8PREP | |
| SCHEMBL6689961 | 0.75 | DPP4 (0.50) | DPP4DPP8PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089362-A1 | 2-CYANOPYRROLES AND THEIR ANALOGUES AS DDP-IV INHIBITORS | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | disclosed |