Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.86 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | ACP1 | P24666 | 2/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PTPRF | P10586 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPRB | P23467 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692673 | 1.00 | PPARG (0.86) | PPARGCA9PTPN1ACP1ENPP2 | |
| SCHEMBL6686162 | 0.95 | PPARG (0.77) | PPARGCA9PTPN1ACP1ENPP2 | |
| SCHEMBL6686160 | 0.95 | PPARG (0.77) | PPARGCA9PTPN1ACP1ENPP2 | |
| SCHEMBL6692956 | 0.88 | PTPN1 (0.74) | PPARGPTPN1ACP1ENPP2MEN1 | |
| SCHEMBL6691628 | 0.88 | PPARG (0.69) | PPARGPTPN1ACP1ENPP2MEN1 | |
| SCHEMBL6691625 | 0.88 | PPARG (0.69) | PPARGPTPN1ACP1ENPP2MEN1 | |
| SCHEMBL6692962 | 0.88 | PTPN1 (0.74) | PPARGPTPN1ACP1ENPP2MEN1 | |
| SCHEMBL6253587 | 0.88 | PPARG (0.69) | PPARGCA9PTPN1ACP1ENPP2 | |
| SCHEMBL6253581 | 0.88 | PPARG (0.69) | PPARGCA9PTPN1ACP1ENPP2 | |
| SCHEMBL6685996 | 0.86 | PPARG (0.67) | PPARGCA9PTPN1ACP1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089276-A2 | THIAZOLIDINEDIONE COMPOUNDS WITH HYPOGLYCEMIC PROPERTIES | CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ (BR) | 2004-10-21 | — | — | WO | claimed |
| WO-2004089276-A2 | THIAZOLIDINEDIONE COMPOUNDS WITH HYPOGLYCEMIC PROPERTIES | CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ (BR) | 2004-10-21 | — | — | WO | disclosed |