Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 17/20 | 0.79 |
| ▸ | PDE4B | Q07343 | 17/20 | 0.79 |
| ▸ | PDE4C | Q08493 | 17/20 | 0.79 |
| ▸ | PDE4D | Q08499 | 17/20 | 0.79 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586085 | 0.88 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4699816 | 0.86 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6683024 | 0.85 | PDE4A (0.74) | PDE4APDE4BPDE4CPDE4DCYP11B1 | |
| SCHEMBL6681398 | 0.84 | PDE4A (0.72) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6683381 | 0.83 | PDE4A (0.71) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6681005 | 0.82 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6683041 | 0.82 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6681009 | 0.82 | PDE4B (0.69) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6589078 | 0.81 | PDE4A (0.72) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6587900 | 0.81 | PDE4A (0.72) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056798-A1 | PHTHALAZINE DERIVATIVES PHOSPHODIESTERASE 4 INHIBITORS | ZAMBON GROUP S.P.A. (IT) | 2004-07-08 | — | — | WO | disclosed |