Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29263702 | 1.00 | POLB (0.38) | POLBTLR7KDM4ETBXAS1HRH1 | |
| SCHEMBL29263704 | 1.00 | POLB (0.38) | POLBTLR7KDM4ETBXAS1HRH1 | |
| SCHEMBL31036006 | 1.00 | POLB (0.38) | POLBTLR7KDM4ETBXAS1HRH1 | |
| SCHEMBL5240745 | 0.98 | POLB (0.39) | POLBTLR7KDM4ETBXAS1HRH1 | |
| SCHEMBL6685246 | 0.92 | POLB (0.40) | POLBKDM4EHDAC3HDAC1HDAC2 | |
| SCHEMBL839885 | 0.83 | — | — | |
| SCHEMBL29530008 | 0.83 | — | — | |
| SCHEMBL28362525 | 0.83 | HSP90AA1 (0.40) | POLBTLR7KDM4EHRH1HDAC3 | |
| SCHEMBL10949970 | 0.82 | HRH1 (0.36) | POLBHRH1HDAC3HDAC1HDAC2 | |
| SCHEMBL16115136 | 0.80 | TDP1 (0.47) | POLBTLR7KDM4ECYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069145-A2 | ANTICANCER COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2004-08-19 | — | — | WO | disclosed |