Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | PPARG | P37231 | 11/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687313 | 1.00 | MEN1 (0.64) | MEN1LMNAKMT2APPARGPTPN1 | |
| SCHEMBL6686210 | 0.86 | MEN1 (0.65) | MEN1LMNAKMT2APPARGPTPN1 | |
| SCHEMBL6686213 | 0.86 | MEN1 (0.65) | MEN1LMNAKMT2APPARGPTPN1 | |
| SCHEMBL6253581 | 0.82 | PPARG (0.69) | MEN1LMNAKMT2APPARGPTPN1 | |
| SCHEMBL6253587 | 0.82 | PPARG (0.69) | MEN1LMNAKMT2APPARGPTPN1 | |
| SCHEMBL6686162 | 0.80 | PPARG (0.77) | MEN1LMNAKMT2APPARGPTPN1 | |
| SCHEMBL6686160 | 0.80 | PPARG (0.77) | MEN1LMNAKMT2APPARGPTPN1 | |
| SCHEMBL6692178 | 0.79 | PPARG (0.58) | MEN1LMNAKMT2APPARGPTPN1 | |
| SCHEMBL6686984 | 0.79 | PPARG (0.58) | MEN1LMNAKMT2APPARGPTPN1 | |
| SCHEMBL6235054 | 0.78 | MEN1 (0.56) | MEN1LMNAKMT2APPARGPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089276-A2 | THIAZOLIDINEDIONE COMPOUNDS WITH HYPOGLYCEMIC PROPERTIES | CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ (BR) | 2004-10-21 | — | — | WO | claimed |
| WO-2004089276-A2 | THIAZOLIDINEDIONE COMPOUNDS WITH HYPOGLYCEMIC PROPERTIES | CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ (BR) | 2004-10-21 | — | — | WO | disclosed |