Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 14/20 | 0.65 |
| ▸ | MEP1B | Q16820 | 5/20 | 0.46 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6037792 | 0.95 | FOLH1 (0.65) | FOLH1MEP1BMEP1A | |
| SCHEMBL5052904 | 0.92 | FOLH1 (0.63) | FOLH1MEP1BMEP1A | |
| SCHEMBL5052882 | 0.91 | FOLH1 (0.65) | FOLH1MEP1BMEP1A | |
| SCHEMBL5054387 | 0.90 | FOLH1 (0.66) | FOLH1MEP1BMEP1A | |
| SCHEMBL5054710 | 0.89 | FOLH1 (0.72) | FOLH1MEP1BMEP1A | |
| SCHEMBL5051109 | 0.88 | FOLH1 (0.67) | FOLH1MEP1BMEP1A | |
| SCHEMBL5060070 | 0.87 | FOLH1 (0.76) | FOLH1MEP1BMEP1A | |
| SCHEMBL5053231 | 0.85 | FOLH1 (0.66) | FOLH1MEP1BMEP1A | |
| SCHEMBL5057858 | 0.84 | FOLH1 (0.65) | FOLH1MEP1BMEP1A | |
| SCHEMBL6037768 | 0.82 | FOLH1 (0.46) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078180-A2 | NAALADASE INHIBITORS FOR TREATING OPIOID TOLERANCE | GUILFORD PHARMACEUTICALS INC. (US) | 2004-09-16 | — | — | WO | claimed |