Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3810567 | 0.70 | MEN1 (0.35) | — | |
| SCHEMBL2577959 | 0.70 | MEN1 (0.35) | — | |
| SCHEMBL28808832 | 0.68 | — | — | |
| SCHEMBL2649990 | 0.68 | SLC6A2 (0.41) | TSHR | |
| SCHEMBL6686063 | 0.68 | CHRM2 (0.30) | — | |
| SCHEMBL7449527 | 0.66 | KCNA5 (0.39) | TSHR | |
| SCHEMBL7447412 | 0.66 | KCNA5 (0.42) | TSHR | |
| SCHEMBL7447627 | 0.65 | KCNA5 (0.45) | TSHR | |
| SCHEMBL96104 | 0.64 | — | — | |
| SCHEMBL4433093 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140871-A4 | THROMBIN OR FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2004-05-06 | — | — | EP | disclosed |
| EP-1140871-A1 | THROMBIN OR FACTOR XA INHIBITORS | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039108-A1 | THROMBIN OR FACTOR XA INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |