Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997178 | 0.82 | MEN1 (0.33) | HDAC6HDAC1HDAC2CA1CA2 | |
| SCHEMBL21877076 | 0.79 | CA14 (0.39) | HDAC6MAPK1HDAC1HDAC2CYP2D6 | |
| SCHEMBL5402224 | 0.79 | MAPK1 (0.37) | HDAC6MAPK1HDAC1HDAC2CYP2D6 | |
| SCHEMBL20215933 | 0.77 | MAPK1 (0.35) | HDAC6MAPK1HDAC1HDAC2CYP2D6 | |
| SCHEMBL23134818 | 0.77 | MAPK1 (0.35) | HDAC6MAPK1HDAC1HDAC2CYP2D6 | |
| SCHEMBL18290052 | 0.76 | MAPK1 (0.34) | HDAC6MAPK1HDAC1HDAC2CYP2D6 | |
| SCHEMBL18329838 | 0.76 | MAPK1 (0.34) | HDAC6MAPK1HDAC1HDAC2CYP2D6 | |
| SCHEMBL19246067 | 0.74 | CA14 (0.36) | HDAC6MAPK1HDAC1HDAC2CYP2D6 | |
| SCHEMBL5404209 | 0.74 | CYP2D6 (0.33) | HDAC6MAPK1HDAC1HDAC2CYP2D6 | |
| SCHEMBL28546389 | 0.73 | HDAC6 (0.35) | HDAC6HDAC1HDAC2L3MBTL1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074335-A1 | NOVEL CATIONIC POLYMERS AND COPOLYMERS, USE THEREOF FOR THE VECTORISATION OF BIOMOLECULES AND SYNTHETIC INTERMEDIATES FOR THE SAME | HALISOL (FR) | 2004-09-02 | — | — | WO | disclosed |
| WO-2004074336-A1 | NOVEL CATIONIC COPOLYMERS, USE THEREOF FOR THE VECTORISATION OF BIOMOLECULES AND SYNTHETIC INTERMEDIATES FOR THE SAME | HALISOL (FR) | 2004-09-02 | — | — | WO | disclosed |