(R,S)-Ampa

(R,S)-Ampa

SCHEMBL6687427

Cc1o[nH]c(=O)c1CC(N)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GRIA1 P42261 4/20 1.00
▸ GRIA3 P42263 4/20 1.00
▸ GRIA4 P48058 4/20 1.00
▸ GRIA2 P42262 3/20 1.00
▸ GRIK5 Q16478 3/20 1.00
▸ MEN1 O00255 3/20 1.00
▸ CYP2C9 P11712 3/20 1.00
▸ CYP2C19 P33261 3/20 1.00
▸ KMT2A Q03164 3/20 1.00
▸ CYP1A2 P05177 3/20 1.00
▸ MAPT P10636 2/20 1.00
▸ GRIK1 P39086 2/20 1.00
▸ CYP2D6 P10635 2/20 1.00
▸ MAPK1 P28482 2/20 1.00
▸ ALDH1A1 P00352 1/20 1.00
▸ TSHR P16473 1/20 1.00
▸ GRIK2 Q13002 1/20 1.00
▸ GRIK3 Q13003 1/20 1.00
▸ GRIK4 Q16099 1/20 1.00
▸ BLM P54132 2/20 0.97

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(S)-Ampa SCHEMBL29407234 1.00 GRIA1 (1.00) GRIA1GRIA3GRIA4GRIA2GRIK5
(R,S)-Ampa SCHEMBL13957590 1.00 GRIA1 (1.00) GRIA1GRIA3GRIA4GRIA2GRIK5
(R,S)-Ampa SCHEMBL29469983 0.98 BLM (1.00) GRIA1GRIA3GRIA4GRIA2GRIK5
SCHEMBL29391008 0.83 GRIA1 (1.00) GRIA1GRIA3GRIA4GRIA2GRIK5
SCHEMBL14948181 0.81 GRIA1 (0.69) GRIA1GRIA3GRIA4GRIA2GRIK5
SCHEMBL31375382 0.80 GRIA1 (1.00) GRIA1GRIA3GRIA4GRIA2GRIK5
SCHEMBL13957587 0.80 GRIA1 (1.00) GRIA1GRIA3GRIA4GRIA2GRIK5
SCHEMBL13972046 0.75 GRIA1 (0.59) GRIA1GRIA3GRIA4GRIA2GRIK5
SCHEMBL13971421 0.75 GRIA1 (0.59) GRIA1GRIA3GRIA4GRIA2GRIK5
SCHEMBL660029 0.74 CYP1A2 (1.00) GRIA1GRIA3GRIA4GRIA2GRIK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3783595-B1 DISPLAY DEVICE AND METHOD OF DRIVING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2026-04-22 — — EP claimed
EP-4619050-A2 DECREASED RETENTION OF MINIPROTEINS IN KIDNEY Aktis Oncology, Inc. (US) 2025-09-24 — — EP claimed
CN-119981030-A Multi-power-head pressurizing stirring pile machine, multi-power-head pressurizing hydraulic system and control method 山河智能装备股份有限公司 2025-05-13 — — CN claimed
CN-119736422-A Taqman multiplex fluorescence quantitative PCR (polymerase chain reaction) detection system and kit for common vibrio pathogens of aquaculture and application and detection method 烟台大学 2025-04-01 — — CN claimed
CN-119673391-A Medical image domain generalization method based on diffusion probability model 济南大学 2025-03-21 — — CN claimed
CN-119554564-A Double-pipe oil gas gathering and transporting system and process for shale oil gas containing wax 中国石油化工集团有限公司 2025-03-04 — — CN claimed
CN-119242259-A Organic silicon pouring sealant and preparation method and application thereof 湖南盛世胶业科技有限公司 2025-01-03 — — CN claimed
CN-115929281-B Water curtain drilling layout method for underground water seal cave depot 中国海洋石油集团有限公司 2024-11-01 — — CN claimed
CN-118791641-A An Ancha polysaccharide capable of targeted increasing lactobacillus, and its preparation method and application 安徽农业大学 2024-10-18 — — CN claimed
CN-118687785-A Simulation test device and method for gas storage sealing system 中国科学院武汉岩土力学研究所 2024-09-24 — — CN claimed
CN-115435458-A Multi-split air conditioning system 青岛海信日立空调系统有限公司 2022-12-06 — — CN claimed
CN-115326309-A Marine LNG (liquefied Natural gas) supply system gas supply pipeline sectional pressure testing device and method 宜昌江峡船用机械有限责任公司 2022-11-11 — — CN claimed
CN-115019846-A Terminal adjuster with high transient response for DDR memory 中国兵器工业集团第二一四研究所苏州研发中心 2022-09-06 — — CN claimed
CN-114690142-A Circular array radar echo data analysis method 南京国睿防务系统有限公司 2022-07-01 — — CN claimed
CN-111239023-B Method for testing rock compression coefficient under high-temperature and high-pressure conditions 西安石油大学 2022-05-20 — — CN claimed
US-11334162-B2 Tactile sensation providing device and method JILIN UNIVERSITY (CN) 2022-05-17 — — US claimed
US-20210177869-A1 METHODS AND COMBINATIONS FOR MODULATING TOLERANCE TO OPIATES, OPIOIDS OR OPIOID ANALGESICS AND TREATING ACUTE AND CHRONIC PAIN CHINA MEDICAL UNIVERSITY (TW) 2021-06-17 — — US claimed
CN-107735094-B New use of inhibitors of cystine-glutamate transporter 中国医药大学 2021-05-28 — — CN claimed
CN-112839679-A Methods and combinations for modulating tolerance to opiates, opioids or opioid analgesics and treating acute and chronic pain 中国医药大学 2021-05-25 — — CN claimed
US-20180153865-A1 NEW USE OF INHIBITOR OF CYSTINE-GLUTAMATE TRANSPORTER CHINA MEDICAL UNIVERSITY (TW) 2018-06-07 — — US claimed
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