Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685585 | 0.93 | ATM (0.49) | ATMCTSDSMN1; SMN2LMNAKDM4E | |
| SCHEMBL6685580 | 0.93 | ATM (0.49) | ATMCTSDSMN1; SMN2LMNAKDM4E | |
| SCHEMBL6690012 | 0.89 | SMN1; SMN2 (0.48) | CTSDSMN1; SMN2LMNAKDM4ETDP1 | |
| SCHEMBL6685493 | 0.85 | ATM (0.48) | ATMCTSDSMN1; SMN2LARS1MRGPRX1 | |
| SCHEMBL6685490 | 0.85 | ATM (0.48) | ATMCTSDSMN1; SMN2LARS1MRGPRX1 | |
| SCHEMBL6690103 | 0.85 | ATM (0.47) | ATMCTSDLARS1KMT2AMRGPRX1 | |
| SCHEMBL6690101 | 0.85 | ATM (0.47) | ATMCTSDLARS1KMT2AMRGPRX1 | |
| SCHEMBL6687571 | 0.82 | MAOB (0.47) | CTSDSMN1; SMN2LMNAKDM4ETDP1 | |
| SCHEMBL6687574 | 0.82 | MAOB (0.47) | CTSDSMN1; SMN2LMNAKDM4ETDP1 | |
| SCHEMBL6686469 | 0.81 | KMT2A (0.53) | ATMCTSDSMN1; SMN2LMNALARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |