Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 11/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.43 |
| ▸ | PREP | P48147 | 4/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687433 | 1.00 | MAPK1 (0.45) | MAPK1KMT2AL3MBTL1DPP4DPP8 | |
| SCHEMBL6691626 | 0.88 | DPP4 (0.45) | DPP4DPP8PREPKLK5 | |
| SCHEMBL6691632 | 0.88 | DPP4 (0.45) | DPP4DPP8PREPKLK5 | |
| SCHEMBL6691637 | 0.88 | DPP4 (0.45) | DPP4DPP8PREPKLK5 | |
| SCHEMBL6689730 | 0.86 | DPP4 (0.44) | DPP4DPP8PREPKLK5 | |
| SCHEMBL6685074 | 0.86 | NPC1 (0.43) | DPP4DPP8PREPKLK5MAPT | |
| SCHEMBL6685077 | 0.86 | NPC1 (0.43) | DPP4DPP8PREPKLK5MAPT | |
| SCHEMBL6685067 | 0.86 | DPP4 (0.46) | DPP4DPP8PREPKLK5 | |
| SCHEMBL6685059 | 0.86 | DPP4 (0.46) | DPP4DPP8PREPKLK5 | |
| SCHEMBL6685656 | 0.82 | DPP4 (0.43) | DPP4DPP8PREPKLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089362-A1 | 2-CYANOPYRROLES AND THEIR ANALOGUES AS DDP-IV INHIBITORS | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | disclosed |