SCHEMBL6687835

SCHEMBL6687835

CC(N)CN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 2/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
CA1 P00915 3/20 0.34
CA14 Q9ULX7 3/20 0.34
CA2 P00918 2/20 0.34
CA12 O43570 2/20 0.34
CA7 P43166 2/20 0.33
NOS1 P29475 2/20 0.33
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
CPB2 Q96IY4 2/20 0.31
CTSK P43235 1/20 0.30
AAK1 Q2M2I8 1/20 0.30
GABRP O00591 2/20 0.30
GABRD O14764 2/20 0.30
GABRA1 P14867 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19891780 0.83 DPP4 (0.37) HDAC6HDAC1HDAC2CA1CA14
SCHEMBL1456149 0.82 HDAC6 (0.38) HDAC6HDAC1HDAC2CA1CA14
SCHEMBL6285478 0.82 HDAC6 (0.34) HDAC6HDAC1HDAC2CA1CA14
SCHEMBL20033588 0.82 HDAC6 (0.38) HDAC6HDAC1HDAC2CA1CA14
SCHEMBL5402224 0.82 MAPK1 (0.37) HDAC6HDAC1HDAC2CA1CA14
SCHEMBL15798179 0.81 HDAC6 (0.33) HDAC6HDAC1HDAC2CA1CA14
SCHEMBL6285387 0.81 HDAC6 (0.33) HDAC6HDAC1HDAC2CA1CA14
SCHEMBL8341453 0.80 HDAC6 (0.35) HDAC6HDAC1HDAC2CA1CA14
SCHEMBL12324239 0.79 HDAC6 (0.36) HDAC6HDAC1HDAC2CA1CA14
SCHEMBL7997176 0.78 MEN1 (0.35) HDAC6HDAC1HDAC2CA1CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004074336-A1 NOVEL CATIONIC COPOLYMERS, USE THEREOF FOR THE VECTORISATION OF BIOMOLECULES AND SYNTHETIC INTERMEDIATES FOR THE SAME HALISOL (FR) 2004-09-02 WO disclosed