Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 10/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699518 | 0.83 | AKR1C3 (0.56) | AKR1C3NR4A2KMT2AKMONPC1 | |
| SCHEMBL25527369 | 0.83 | AKR1C3 (0.56) | AKR1C3NR4A2KMT2AKMONPC1 | |
| SCHEMBL6691398 | 0.83 | AKR1C3 (0.56) | AKR1C3NR4A2KMT2AKMONPC1 | |
| SCHEMBL4250289 | 0.83 | KMT2A (0.61) | AKR1C3NR4A2KMT2AKMONPC1 | |
| SCHEMBL6693659 | 0.83 | AKR1C3 (0.56) | AKR1C3NR4A2KMT2AKMONPC1 | |
| SCHEMBL29492633 | 0.83 | KMT2A (0.61) | AKR1C3NR4A2KMT2AKMONPC1 | |
| SCHEMBL10586172 | 0.83 | AKR1C3 (0.56) | AKR1C3NR4A2KMT2AKMONPC1 | |
| SCHEMBL8470183 | 0.81 | AKR1C3 (0.54) | AKR1C3NR4A2KMT2AKMONPC1 | |
| SCHEMBL11557990 | 0.80 | KMT2A (0.62) | AKR1C3NR4A2KMT2ANPC1RAB9A | |
| SCHEMBL25527238 | 0.80 | FOLH1 (0.54) | AKR1C3NR4A2KMT2AKMONPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950669-B1 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM & HAAS (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6306991-B1 | TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS | ROHM AND HAAS COMPANY | 2001-10-23 | — | — | US | disclosed |
| US-6149977-A | CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. | ROHM AND HAAS COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| EP-0950669-A2 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM AND HAAS COMPANY (US) | 1999-10-20 | — | — | EP | disclosed |