⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbimide SCHEMBL3149105 | 0.92 | KDM4E (0.30) | — | |
| Carbimide SCHEMBL5167749 | 0.89 | — | — | |
| SCHEMBL338264 | 0.85 | KDM4E (0.34) | — | |
| SCHEMBL1123 | 0.85 | — | — | |
| SCHEMBL785147 | 0.85 | — | — | |
| SCHEMBL23174460 | 0.82 | — | — | |
| SCHEMBL21409686 | 0.82 | — | — | |
| Phosphine SCHEMBL19611314 | 0.82 | — | — | |
| SCHEMBL21409683 | 0.82 | — | — | |
| SCHEMBL21409789 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040156859-A1 | GP-41 peptides, BBB peptides, anticancer agents, antihistamines, bronchodilators, hypotensive agents, antiangina agents, opioids, analgesics, antidepressants, and hypothyroid agents reactive with amino, hydroxyl or thiol groups | CONJUCHEM, INC. (CA) | 2004-08-12 | — | — | US | disclosed |
| US-6706892-B1 | ADMINSTERING MALEIMIDE DERIVATIVE TO COVALENTLY BOND PROTEIN; WOUND HEALING, ANTIBIOTIC, ANTIINFLAMMATORY, ANTICARCINOGENIC, HYPOTENSIVE, AND ANALGESIC AGENTS | CONJUCHEM, INC. (CA) | 2004-03-16 | — | — | US | disclosed |
| US-20030170250-A1 | Local delivery of long lasting therapeutic agents | EZRIN ALAN M (US) | 2003-09-11 | — | — | US | disclosed |
| EP-1235618-A2 | BIOCONJUGATION IN VIVO TO PULMONARY OR BLOOD COMPONENTS | Conjuchem, Inc. (CA) | 2002-09-04 | — | — | EP | disclosed |
| US-20020018751-A1 | CELLULAR AND SERUM PROTEIN ANCHORS FOR DIAGNOSTIC IMAGING | CONJUCHEM, INC. (CA) | 2002-02-14 | — | — | US | disclosed |
| WO-2001017568-A2 | BIOCONJUGATION IN VIVO TO PULMONARY OR BLOOD COMPONENTS | CONJUCHEM, INC. (CA) | 2001-03-15 | — | — | WO | disclosed |
| EP-1042003-A1 | DELIVERY OF LONG LASTING THERAPEUTIC AGENTS BY FORMING COVALENT ATTACHMENTS IN VIVO | Conjuchem, Inc. (CA) | 2000-10-11 | — | — | EP | disclosed |
| US-6107489-A | CHEMICALLY REACTIVE TRIPEPTIDE INTERMEDIATES WHICH CAN REACT WITH AVAILABLE REACTIVE FUNCTIONALITIES ON BLOOD COMPONENTS TO FORM COVALENT LINKAGES, THE RESULTING CONJUGATES HAVE RENIN INHIBITION ACTIVITY FOR EXTENDED PERIODS OF TIME | CONJUCHEM, INC. (CA) | 2000-08-22 | — | — | US | disclosed |
| WO-1999048536-A2 | DELIVERY OF LONG LASTING THERAPEUTIC AGENTS BY FORMING COVALENT ATTACHMENTS IN VIVO | CONJUCHEM, INC. (CA) | 1999-09-30 | — | — | WO | disclosed |