Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689410 | 1.00 | GFER (0.59) | GFERMAPTKDM4EPIM1TDP1 | |
| SCHEMBL6690508 | 0.85 | GFER (0.42) | GFERMAPTKDM4EPIM1ALOX15 | |
| SCHEMBL6684235 | 0.85 | GFER (0.42) | GFERMAPTKDM4EPIM1ALOX15 | |
| SCHEMBL6695622 | 0.82 | GFER (0.63) | GFERMAPTKDM4EPIM1TDP1 | |
| SCHEMBL4972251 | 0.77 | GFER (0.94) | GFERMAPTKDM4EPIM1TDP1 | |
| SCHEMBL3941869 | 0.75 | GFER (1.00) | GFERMAPTKDM4EPIM1TDP1 | |
| SCHEMBL30317424 | 0.75 | GFER (1.00) | GFERMAPTKDM4EPIM1TDP1 | |
| SCHEMBL6683286 | 0.73 | GFER (0.97) | GFERMAPTKDM4EPIM1TDP1 | |
| SCHEMBL4281540 | 0.73 | KDM4E (0.44) | GFERMAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL4281532 | 0.73 | KDM4E (0.44) | GFERMAPTKDM4EHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063156-A1 | NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS | BIOVITRUM AB (SE) | 2004-07-29 | — | — | WO | claimed |
| WO-2004063156-A1 | NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS | BIOVITRUM AB (SE) | 2004-07-29 | — | — | WO | disclosed |