Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.65 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23392538 | 0.95 | HDAC1 (0.72) | HDAC1HDAC2MEN1KMT2AKDM4E | |
| SCHEMBL6680296 | 0.95 | HDAC1 (0.72) | HDAC1HDAC2MEN1KMT2AKDM4E | |
| SCHEMBL6691310 | 0.90 | PTGS1 (0.76) | HDAC1HDAC2MEN1KMT2AKDM4E | |
| SCHEMBL23392572 | 0.90 | PTGS1 (0.76) | HDAC1HDAC2MEN1KMT2AKDM4E | |
| SCHEMBL23392575 | 0.90 | HDAC1 (0.75) | HDAC1HDAC2MEN1KMT2AKDM4E | |
| SCHEMBL6688392 | 0.89 | KMT2A (0.65) | HDAC1HDAC2MEN1KMT2AKDM4E | |
| SCHEMBL6686099 | 0.86 | MAPT (0.55) | HDAC1HDAC2MEN1KMT2AKDM4E | |
| SCHEMBL23392577 | 0.85 | HDAC1 (0.66) | HDAC1HDAC2MEN1KMT2AKDM4E | |
| SCHEMBL23392576 | 0.85 | HDAC1 (0.66) | HDAC1HDAC2MEN1KMT2AKDM4E | |
| SCHEMBL6685305 | 0.85 | MEN1 (0.60) | HDAC1HDAC2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |