Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668805 | 0.95 | DPP4 (0.65) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL4667792 | 0.94 | DPP4 (0.68) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL4668920 | 0.90 | DPP4 (0.67) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL4667112 | 0.89 | DPP4 (0.75) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL4669749 | 0.89 | DPP4 (0.75) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL4667827 | 0.86 | DPP4 (0.68) | DPP4CHRM1 | |
| SCHEMBL4668815 | 0.86 | DPP4 (0.78) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL4668817 | 0.86 | DPP4 (0.78) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL4668591 | 0.86 | DPP4 (0.66) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL14257950 | 0.84 | DPP4 (0.62) | DPP4CHRM1CHRM2CHRM3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004033455-A2 | HEMISUCCINATE SALTS OF HETEROCYCLIC DPP-IV INHIBITORS | NOVO NORDISK A/S (DK) | 2004-04-22 | — | — | WO | disclosed |