⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21069936 | 1.00 | — | — | |
| SCHEMBL21070848 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL3945988 | 0.98 | SLC6A4 (0.36) | — | |
| SCHEMBL25081018 | 0.88 | HTR2A (0.33) | — | |
| Propionic Acid SCHEMBL72914 | 0.85 | SLC6A2 (0.36) | — | |
| SCHEMBL168891 | 0.82 | SLC6A2 (0.37) | — | |
| SCHEMBL873427 | 0.79 | — | — | |
| SCHEMBL4608713 | 0.79 | — | — | |
| SCHEMBL1777157 | 0.79 | — | — | |
| SCHEMBL8742282 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118904863-A | Recycling method of polyester cotton spandex blended fabric | 青岛阿脒诺材料技术有限公司 | 2024-11-08 | — | — | CN | claimed |
| CN-118893071-A | Method for recycling polyester cotton blended fabric | 青岛阿脒诺材料技术有限公司 | 2024-11-05 | — | — | CN | claimed |
| CN-118598813-B | L-malic acid salsa Mi Duofen and preparation method thereof | 山东齐都药业有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-118598813-A | L-malic acid salsa Mi Duofen and preparation method thereof | 山东齐都药业有限公司 | 2024-09-06 | — | — | CN | claimed |
| US-20240150326-A1 | CARBOXAMIDE COMPOUNDS AND USES THEREOF | INCYTE CORPORATION | 2024-05-09 | — | — | US | claimed |
| CN-112292380-B | N- (phenyl) -2- (phenyl) pyrimidine-4-carboxamide derivatives and related compounds as HPK1 inhibitors for the treatment of cancer | 因赛特公司 | 2024-04-05 | — | — | CN | claimed |
| EP-3755703-B1 | N-(PHENYL)-2-(PHENYL)PYRIMIDINE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS HPK1 INHIBITORS FOR TREATING CANCER | INCYTE CORP (US) | 2022-05-04 | — | — | EP | claimed |
| CN-112292380-A | N- (phenyl) -2- (phenyl) pyrimidine-4-carboxamide derivatives and related compounds as HPK1 inhibitors for the treatment of cancer | 因赛特公司 | 2021-01-29 | — | — | CN | claimed |
| EP-3755703-A1 | N-(PHENYL)-2-(PHENYL)PYRIMIDINE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS HPK1 INHIBITORS FOR TREATING CANCER | Incyte Corporation (US) | 2020-12-30 | — | — | EP | claimed |
| WO-2019164846-A1 | N-(PHENYL)-2-(PHENYL)PYRIMIDINE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS HPK1 INHIBITORS FOR TREATING CANCER | INCYTE CORPORATION (US) | 2019-08-29 | — | — | WO | claimed |
| CN-104945540-A | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORP | 2015-09-30 | — | — | CN | claimed |
| CN-101874044-A | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORP | 2010-10-27 | — | — | CN | claimed |
| CN-119156440-A | Cleaning agent, cleaning method and replenishing liquid | MEC股份有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-118904863-A | Recycling method of polyester cotton spandex blended fabric | 青岛阿脒诺材料技术有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-118893071-A | Method for recycling polyester cotton blended fabric | 青岛阿脒诺材料技术有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-118598813-B | L-malic acid salsa Mi Duofen and preparation method thereof | 山东齐都药业有限公司 | 2024-10-29 | — | — | CN | disclosed |
| US-4584299-A | MIXTURE OF HYPOTENSIVE AND CARDIOTONIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1986-04-22 | — | — | US | disclosed |
| EP-0139053-A1 | Nitriles and primary amines from primary alcohols | TEXACO DEVELOPMENT CORPORATION (US) | 1985-05-02 | — | — | EP | disclosed |
| US-4415755-A | CONTINUOUS VAPOR-PHASE REDUCTIVE AMINATION USING A COPPER CHROMITE CATALYST | TEXACO INC. (US) | 1983-11-15 | — | — | US | disclosed |
| US-4062956-A | Substituted 2-(2-hydroxyethyl)tetrahydro-1,4 oxazines and quaternary salts thereof useful for treating spasmodic syndromes | CENTRE EUROPEEN DE RECHERCHES MAUVERNAY (FR) | 1977-12-13 | — | — | US | disclosed |