Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689984 | 1.00 | SCN9A (0.48) | SCN9APOLBITGA4MAOBMAOA | |
| SCHEMBL6685112 | 0.93 | SCN9A (0.53) | SCN9AMAOBMAOA | |
| SCHEMBL6685108 | 0.93 | SCN9A (0.53) | SCN9AMAOBMAOA | |
| SCHEMBL6685519 | 0.86 | SCN9A (0.55) | SCN9AITGA4MAOBMAOA | |
| SCHEMBL6685522 | 0.86 | SCN9A (0.55) | SCN9AITGA4MAOBMAOA | |
| SCHEMBL6688809 | 0.86 | SCN9A (0.55) | SCN9AITGA4MAOBMAOA | |
| SCHEMBL6689256 | 0.86 | SCN9A (0.53) | SCN9APOLBMAOBMAOAHPGD | |
| SCHEMBL6689254 | 0.86 | SCN9A (0.53) | SCN9APOLBMAOBMAOAHPGD | |
| SCHEMBL6687864 | 0.86 | MAOB (0.45) | POLBITGA4MAOBMAOAITGB1 | |
| SCHEMBL6687860 | 0.86 | MAOB (0.45) | POLBITGA4MAOBMAOAITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |