Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.52 |
| ▸ | DPP4 | P27487 | 13/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685656 | 0.90 | DPP4 (0.43) | PREPDPP4DPP8KLK5DPP9 | |
| SCHEMBL6685659 | 0.90 | DPP4 (0.43) | PREPDPP4DPP8KLK5DPP9 | |
| SCHEMBL6693374 | 0.90 | DPP4 (0.49) | PREPDPP4DPP8KLK5FAP | |
| SCHEMBL6687415 | 0.88 | PREP (0.53) | PREPDPP4DPP8FAPDPP9 | |
| SCHEMBL6685074 | 0.87 | NPC1 (0.43) | PREPDPP4DPP8KLK5DPP9 | |
| SCHEMBL6685077 | 0.87 | NPC1 (0.43) | PREPDPP4DPP8KLK5DPP9 | |
| SCHEMBL6686147 | 0.85 | DPP4 (0.44) | PREPDPP4DPP8KLK5FAP | |
| SCHEMBL6686150 | 0.85 | DPP4 (0.44) | PREPDPP4DPP8KLK5FAP | |
| SCHEMBL6689730 | 0.84 | DPP4 (0.44) | PREPDPP4DPP8KLK5 | |
| SCHEMBL6689672 | 0.84 | DPP4 (0.46) | PREPDPP4DPP8KLK5DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089362-A1 | 2-CYANOPYRROLES AND THEIR ANALOGUES AS DDP-IV INHIBITORS | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | disclosed |