Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28932443 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL372447 | 1.00 | — | — | |
| Bicarbonate SCHEMBL3686171 | 1.00 | — | — | |
| Bicarbonate SCHEMBL919436 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL3342060 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL14563498 | 0.94 | — | — | |
| Bicarbonate SCHEMBL537207 | 0.93 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL11308402 | 0.93 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL4437082 | 0.93 | — | — | |
| Bicarbonate SCHEMBL168136 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122057522-A | Nickel-based catalyst based on bi-metal solid solution oxide as carrier, preparation method and application thereof in hydrogen production | 吉林大学 | 2026-05-19 | — | — | CN | claimed |
| WO-2025107372-A1 | METHOD FOR SYNTHESIZING CYCLIC CARBONATE BY UREA ALCOHOLYSIS | 惠州市绿色能源与新材料研究院 | 2025-05-30 | — | — | WO | claimed |
| CN-118834440-A | Modified opal, silicone rubber-modified opal composite material, and preparation method and application thereof | 新疆大学 | 2024-10-25 | — | — | CN | claimed |
| CN-117586219-A | Method for synthesizing cyclic carbonate by alcoholysis of urea | 惠州市绿色能源与新材料研究院 | 2024-02-23 | — | — | CN | claimed |
| CN-122057522-A | Nickel-based catalyst based on bi-metal solid solution oxide as carrier, preparation method and application thereof in hydrogen production | 吉林大学 | 2026-05-19 | — | — | CN | disclosed |
| WO-2025107372-A1 | METHOD FOR SYNTHESIZING CYCLIC CARBONATE BY UREA ALCOHOLYSIS | 惠州市绿色能源与新材料研究院 | 2025-05-30 | — | — | WO | disclosed |
| CN-118834440-A | Modified opal, silicone rubber-modified opal composite material, and preparation method and application thereof | 新疆大学 | 2024-10-25 | — | — | CN | disclosed |
| CN-117586219-A | Method for synthesizing cyclic carbonate by alcoholysis of urea | 惠州市绿色能源与新材料研究院 | 2024-02-23 | — | — | CN | disclosed |
| CN-116876027-A | Electrolytic water catalyst and preparation method and application thereof | 山西迎润新能源有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-113666382-A | Preparation method of nano rare earth hexaboride | 江西善纳新材料科技有限公司 | 2021-11-19 | — | — | CN | disclosed |
| EP-1257377-A4 | RAPID CONVERSION OF METAL-CONTAINING COMPOUNDS TO FORM METALS OR METAL OXIDES | OMG AMERICAS INC (US) | 2004-04-21 | — | — | EP | disclosed |
| US-6689191-B2 | DECOMPOSITION, OXIDATION, AND REDUCTION; CAN BE SIMULTANEOUS | OMG AMERICAS, INC. | 2004-02-10 | — | — | US | disclosed |
| US-20030019328-A1 | Rapid conversion of metal-containing compounds to form metals or metal oxides | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2003-01-30 | — | — | US | disclosed |
| EP-1257377-A1 | RAPID CONVERSION OF METAL-CONTAINING COMPOUNDS TO FORM METALS OR METAL OXIDES | OMG Americas, Inc. (US) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001062421-A1 | RAPID CONVERSION OF METAL-CONTAINING COMPOUNDS TO FORM METALS OR METAL OXIDES | OMG AMERICAS, INC. (US) | 2001-08-30 | — | — | WO | disclosed |
| US-5679235-A | MIXTURE OF TETRAVALENT TITANIUM AND TRIVALENT CERIUM SALTS DISSOLVED IN SOLUTION OF METHANESULFONIC ACID AT SPECIFIED CONCENTRATION | HYDRO-QUEBEC (CA) | 1997-10-21 | — | — | US | disclosed |
| US-5409581-A | Reduction of organic compounds in methanesulfonic acid | HYDRO-QUEBEC (CA) | 1995-04-25 | — | — | US | disclosed |
| EP-0628094-A1 | TETRAVALENT TITANIUM ELECTROLYTE AND TRIVALENT TITANIUM REDUCING AGENT OBTAINED THEREBY | HYDRO-QUEBEC (CA) | 1994-12-14 | — | — | EP | disclosed |
| US-5246553-A | Redox system | HYDRO-QUEBEC (CA) | 1993-09-21 | — | — | US | disclosed |
| WO-1993018207-A1 | TETRAVALENT TITANIUM ELECTROLYTE AND TRIVALENT TITANIUM REDUCING AGENT OBTAINED THEREBY | HYDRO-QUEBEC (CA) | 1993-09-16 | — | — | WO | disclosed |