Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13790123 | 1.00 | NR1I2 (0.41) | NR1I2ALBPDE4DIRAK4ABCB1 | |
| SCHEMBL6691481 | 1.00 | NR1I2 (0.41) | NR1I2ALBPDE4DIRAK4ABCB1 | |
| SCHEMBL332026 | 1.00 | NR1I2 (0.41) | NR1I2ALBPDE4DIRAK4ABCB1 | |
| SCHEMBL18480735 | 0.87 | NR1I2 (0.33) | NR1I2ALBPDE4D | |
| SCHEMBL13789991 | 0.87 | NR1I2 (0.39) | NR1I2ALBPDE4DIRAK4 | |
| SCHEMBL20616297 | 0.85 | NR1I2 (0.32) | NR1I2ALBPDE4D | |
| SCHEMBL5117081 | 0.83 | NR1I2 (0.37) | NR1I2ALBPDE4DIRAK4 | |
| SCHEMBL14049050 | 0.83 | NR1I2 (0.37) | NR1I2ALBPDE4DIRAK4 | |
| SCHEMBL4980179 | 0.83 | NR1I2 (0.37) | NR1I2ALBPDE4DIRAK4 | |
| SCHEMBL331086 | 0.83 | NR1I2 (0.37) | NR1I2ALBPDE4DIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100465174-C | Process for preparing optics pure abacavir | SHANGHAI INST ORGANIC CHEM (CN) | 2009-03-04 | — | — | CN | disclosed |
| CN-1861601-A | Process for preparing optics pure abacavir | SHANGHAI INST ORGANIC CHEM (CN) | 2006-11-15 | — | — | CN | disclosed |
| EP-0878548-B1 | Multistep process for the preparation of (1S,4R)- and/or (1R,4S)-4-(2-Amino-6-Chlor-9-H-purin-9-yl)-2-cyclopentene-1-methanol | LONZA AG (CH) | 2004-09-01 | — | — | EP | disclosed |
| EP-1124805-B1 | METHOD FOR PRODUCING 4-[(2',5'- DIAMINO-6'- HALOPYRIMIDINE- 4'-YL)AMINO]- CYCLOPENT- 2-ENYLMETHANOLS | LONZA AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| US-6433170-B1 | ETHERIFICATION OF A CORRSPONDING CHEMICAL INTERMEDIATE | LONZA GROUP (CH) | 2002-08-13 | — | — | US | disclosed |
| EP-0434450-B1 | Therapeutic nucleosides | WELLCOME FOUND (GB) | 1999-07-07 | — | — | EP | disclosed |
| EP-0921121-A1 | Intermediates to therapeutic nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1999-06-09 | — | — | EP | disclosed |
| EP-0921114-A1 | Intermediates to therapeutic nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1999-06-09 | — | — | EP | disclosed |
| EP-0349242-B1 | Therapeutic nucleosides | WELLCOME FOUND (GB) | 1995-03-22 | — | — | EP | disclosed |
| EP-0434450-A2 | Therapeutic nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |
| EP-0349242-A2 | Therapeutic nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-01-03 | — | — | EP | disclosed |