Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6694825 | 0.99 | DPP4 (0.40) | DPP4DPP8DPP9CTSC | |
| SCHEMBL1071104 | 0.78 | DPP4 (0.57) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL6168108 | 0.77 | DPP4 (0.56) | DPP4DPP8DPP9 | |
| SCHEMBL8295955 | 0.77 | DPP4 (0.67) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL6168195 | 0.76 | DPP4 (0.65) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL6823557 | 0.76 | DPP4 (0.65) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL6918367 | 0.75 | DPP4 (0.67) | DPP4DPP8DPP9 | |
| SCHEMBL8295957 | 0.75 | DPP4 (0.63) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL6171974 | 0.73 | DPP4 (0.47) | DPP4 | |
| Hydrochloric Acid SCHEMBL6167671 | 0.73 | DPP4 (0.46) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071454-A2 | SUBSTITUTED AZETIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | GUILFORD PHARMACEUTICALS INC. (US) | 2004-08-26 | — | — | WO | disclosed |
| WO-2004071454-A2 | SUBSTITUTED AZETIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | GUILFORD PHARMACEUTICALS INC. (US) | 2004-08-26 | — | — | WO | disclosed |