Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.61 |
| ▸ | HTR2B | P41595 | 3/20 | 0.61 |
| ▸ | HTR2C | P28335 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.52 |
| ▸ | ACP3 | P15309 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3981772 | 0.88 | HTR2A (0.58) | HTR2AHTR2BHTR2CMAPTADRA2C | |
| SCHEMBL4436742 | 0.87 | HTR2A (0.51) | HTR2AHTR2BHTR2CMAPTADRA2C | |
| SCHEMBL31273982 | 0.87 | HTR2A (0.60) | HTR2AHTR2BHTR2CMAPTADRA2C | |
| SCHEMBL3470487 | 0.87 | HTR2A (0.60) | HTR2AHTR2BHTR2CMAPTADRA2C | |
| SCHEMBL13235906 | 0.86 | HTR2A (0.64) | HTR2AHTR2BHTR2CMAPTADRA2C | |
| SCHEMBL19943590 | 0.86 | HTR2A (0.69) | HTR2AHTR2BHTR2CMAPTADRA2C | |
| SCHEMBL16131653 | 0.86 | HTR2A (0.69) | HTR2AHTR2BHTR2CMAPTADRA2C | |
| SCHEMBL27740625 | 0.84 | EPHX1 (0.62) | HTR2AHTR2BHTR2CMAPTADRA2C | |
| SCHEMBL28017508 | 0.83 | HTR2A (0.56) | HTR2AHTR2BHTR2CMAPTADRA2C | |
| SCHEMBL24780249 | 0.83 | EPHX1 (0.49) | HTR2AHTR2BHTR2CMAPTADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096808-A1 | TRIAZINE COMPOUNDS AND THEIR USE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |